Members of the Skeletal Muscle Plasticity and Regeneration Laboratory (SMPRL), led by Sarah Greising, PhD, assistant professor in the School of Kinesiology, attended and presented research at the American Physiological Society’s Integrative Physiology of Exercise 2020 conference, held virtually this year November 9-13. 

Postdoctoral fellow Dr. Jacob Sorensen was selected to give an oral presentation, entitled “Secondary denervation and poor neuromuscular junction remodeling is a chronic pathophysiologic consequence of volumetric muscle loss.” This work provides evidence that volumetric muscle loss injury has a negative impact on the remaining neuromuscular junctions. Furthermore, denervation combined with a poor neuromuscular junction remodeling likely contributes to the long-term loss of muscle function and regenerative capacity following injury. 

Postdoctoral fellow Dr. Christiana Raymond-Pope presented a poster, entitled “Diminished metabolic rate following traumatic orthopaedic injury may predispose chronic disease development.” This work evaluated the impact of traumatic injury on physical activity and whole-body metabolism, and evaluated how restricted activity a model of bedrest affects these physiologic aspects.

Kinesiology Honors Undergraduate Alec Basten completed his thesis presentation requirement in a poster presentation, entitled “Chronic oxidative dysfunction following volumetric muscle loss injury.” This work systematically reviewed prior work on chronic comorbidities of skeletal muscle following volumetric muscle loss injury; and evaluated how injuries impairs the capillarity and oxidative skeletal muscle capacity chronically.

Co-authors of the collective work include SMPRL lab members Kyle Dalske, Daniel Hoffman, as well as research collaborators Dr. Benjamin Corona and Dr. Jarrod Call from Wake Forest University and University of Georgia, respectively. 

Learn more about the meeting here.