Sarah M Greising, PhD, assistant professor in the School of Kinesiology and director of the Skeletal Muscle Plasticity and Regeneration Laboratory (SMPRL), has published an article with colleagues including current Kinesiology MS student Kyle Dalske in Tissue Engineering, Part A.

The paper is titled Pharmacological Mitigation of Fibrosis in a Porcine Model of Volumetric Muscle Loss Injury. It thoroughly evaluated the effect of a clinically available anti-fibrotic therapy on the development of fibrosis after volumetric muscle loss injury in a large animal model. The most salient finding of the study is that the anti-fibrotic nintedanib significantly reduced the development of VML injury-induced fibrous tissue deposition and stiffness.

The full citation is as follows: Corona, B.T., Rivera, J.C., Dalske K.A., Wenke, J.C., & Greising, S. M. (In Press, 2019). Pharmacological Mitigation of Fibrosis in a Porcine Model of Volumetric Muscle Loss Injury. Tissue Engineering, Part A. https://doi.org/10.1089/ten.TEA.2019.0272